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Rosetta Genomics Announces Agreement With Global Pharmaceutical Company to Advance   - 3 Hours ago
PRINCETON, NJ and REHOVOT, ISRAEL -- (Marketwired) -- 07/31/14 -- Rosetta Genomics Ltd "Earlier diagnosis of Alzheimer's disease is critical to the development of new, effective therapeutics that can

Genomic Health to Announce Second Quarter 2014 Financial Results and Host Conference   - 3 Hours ago
PR Newswire REDWOOD CITY, Calif., July 31, 2014 REDWOOD CITY, Calif. , July 31, 2014 /PRNewswire/ -- Genomic Health, Inc. (Nasdaq: GHDX) today announced that the company will host a conference

BioNano Genomics Announces the Purchase of the Irys System by BGI   - 3 Hours ago
PR Newswire SAN DIEGO and SHENZHEN, China, July 31, 2014 SAN DIEGO and SHENZHEN, China , July 31, 2014 /PRNewswire/ -- BioNano Genomics announced today the purchase of an Irys ™ System by BGI ,

Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single   - 3 Hours ago
1 Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK 2 Department of Oncology, University of Cambridge, Cambridge, UK 3 Centre for

Double GC:GC Mismatch in dsDNA Enhances Local Dynamics Retaining the DNA Footprint:   - 3 Hours ago
Abstract Mutations in the genome are responsible for several fatal genetic disorders. The default DNA repair mechanism restores the malfunction of the gene caused by mutation to maintain functional

Arsenic induces apoptosis by the lysosomal-mitochondrial pathway in INS-1 cells   - 3 Hours ago
ABSTRACT Recently, long term arsenic exposure was considered to be associated with an increased risk of diabetes mellitus. While a relation of cause-and-effect between apoptosis of pancreatic ß-cells

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Phosphoserine phosphatase (PSPH) gene mutation in an intellectual disability family   - 4 Hours ago
How to Cite Vincent, J.B., Jamil, T., Rafiq, M.A., Anwar, Z., Ayaz, M., Hameed, A., Nasr, T., Naeem, F., Khattak, N.A., Carter, M., Ahmed, I., John, P., Wiame, E., Andrade, D.M., Schaftingen, E.V., Mir,

23andMe Lands Grant From NIH to Detect Genetic Roots for Disease   - 15 Hours ago
Reuters Health Information By Reuters Staff July 30, 2014 WASHINGTON D.C. (Reuters) - Home genetics startup 23andMe has secured a $1.4 million two-year grant from the National Institutes of Health
all 3 news articles >>

SUMO-1 plays crucial roles for spindle organization, chromosome congression, and   - 10 Hours ago
Summary S mall u biquitin-related mo difier-1 (SUMO-1)-dependent modifications of many target proteins are involved in a range of intracellular processes. Previous studies reported the localization

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Boveri at 100: Theodor Boveri and Genetic Predisposition To Cancer   - 11 Hours ago
Abstract: A hundred years have passed since the publication of Theodore Boveri's Zur Frage der Entstehung maligner Tumoren (‘Concerning the Origin of Malignant Tumours’). This prescient publication

Between the beginning of last year and early April 2014, 11 different companies   - 12 Hours ago
(live-PR.com) - As recently noted by Forbes, the biotech bull market of 2013 has helped to revive an approach to drug development that had become largely abandoned and pursued by only a few devoted believers.

From the Human Genome to the Human Proteome   - 12 Hours ago
A.J.R.H. acknowledges continuous support to the Netherlands Proteomics Center by the Netherlands Organization for Scientific Research (NWO) supported large-scale proteomics facility Proteins@Work (project

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Logic Gating by Macrocycle Displacement Using a Double-Stranded DNA [3]Rotaxane   - 12 Hours ago
Abstract Molecular interlocked systems with mechanically trapped components can serve as versatile building blocks for dynamic nanostructures. Here we report the synthesis of unprecedented double-stranded

Replication stress is a potent driver of functional decline in ageing haematopoietic   - 13 Hours ago
Haematopoietic stem cells (HSCs) self-renew for life, thereby making them one of the few blood cells that truly age 1 , 2 . Paradoxically, although HSCs numerically expand with age, their functional activity

Clonal evolution in breast cancer revealed by single nucleus genome sequencing   - 13 Hours ago
Sequencing studies of breast tumour cohorts have identified many prevalent mutations, but provide limited insight into the genomic diversity within tumours. Here we developed a whole-genome and exome

Ageing: Old blood stem cells feel the stress   - 13 Hours ago
doi:10.1038/nature13652 Authors: Jiri Bartek & Zdenek Hodny Ageing is accompanied by deterioration in the haematopoietic stem cells that are responsible for regenerating the blood system. Cellular

'Myths & Lies' That Threaten Our Schools: An Interview With David Berliner & Gene   - 13 Hours ago
This summer, I'll be alternating between publishing thematic collections of past posts (ones on Student Motivation, Implementing The Common Core,   Teaching Reading & Writing ,  Parent Involvement ,

Genes Found Essential in Other Mycoplasmas Are Dispensable in Mycoplasma bovis   - 13 Hours ago
Source: PloS One  |  Posted 4 weeks ago ; Sharma S, Markham P, Browning G; PloS One 9 (6), e97100 (2014) Mycoplasmas are regarded to be useful models for studying the minimum genetic complement required

Cancer stem cells: From concept to cure   - 14 Hours ago
Cell & Molecular Biology > Cell & Molecular Biology > STEM CELLS > Accepted Articles >

Type II interferon promotes differentiation of myeloid-biased hematopoietic stem   - 14 Hours ago
Abstract Interferon gamma (IFN?) promotes cell division of hematopoietic stem cells (HSCs) without affecting the total HSC number. We postulated that IFN? stimulates differentiation of HSCs as part

Genomic instability in human stem cells: Current status and future challenges   - 14 Hours ago
Abstract Genomic instability is recognized as one of the most important hurdles in the expanding field of stem cell-based therapies. In the recent years, an accumulating body of evidence has shown that

Endothelial interleukin-6 defines the tumorigenic potential of primary human cancer   - 14 Hours ago
Abstract Head and neck squamous cell carcinomas (HNSCC) contain a small sub-population of stem cells endowed with unique capacity to generate tumors. These cancer stem cells (CSC) are localized in perivascular

U.S. study: genes have a role in choosing friends   - 15 Hours ago
Egypt 'strongly condemns' Israeli shelling of Gaza market, UN schoolVIDEO: Salah scores in Chelsea friendly English Premier League to use vanishing spray in matches Egypt's Hammoudi completes move to

The embryonic expression of EphA receptor genes in mice supports their candidacy   - 15 Hours ago
Abstract Background Eph receptors, comprising the A- and B- subfamilies, are the largest family of receptor tyrosine kinases in the mammalian genome, and their function is critical for morphogenesis

A simple metric of promoter architecture robustly predicts expression breadth of   - 15 Hours ago
Conventional wisdom holds that, owing to the dominance of features such as chromatin level control, the expression of a gene cannot be readily predicted from knowledge of promoter architecture. This is
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